The zodiac four, which endures the off-season worse than others. Cancer.

If Cancers can't stand changing moon phases... what can we say about the off-season. During the period when spring turns into summer, all existing (and fictional) diseases stick to them. And on the days when winter turns into spring, Cancers fall from fatigue. Smart aquatic creatures aren't looking for a cure for depression—they're just waiting for the off-season to end (and lashing out in between).