Biotechnology.

February 7, 2023

Biotechnologists have grown small human intestines inside mice, pea-sized organelles that allow researchers to study the immune function of the gastrointestinal tract without human experiments. Mini-guts were created from stem cells obtained from human blood and skin. The scientists injected a special molecular cocktail into the cells and in four weeks grew spheres several millimeters in diameter. They were transplanted into mice with suppressed immunity - so that there would be no rejection. Already in the body of rodents, after the intervention of scientists, organelles began to produce human immune cells. After 20 weeks, the mini-guts contained 20 types of them. With this model, researchers will be able to study disorders of the gastrointestinal tract that provoke ulcerative colitis, Crohn's disease and other health problems.